Librería Biogea PRINCIPLES OF ANIMAL RESEARCH FOR GRADUATE AND UNDERGRADUATE STUDENTS

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PRINCIPLES OF ANIMAL RESEARCH FOR GRADUATE AND UNDERGRADUATE STUDENTS
Título:
PRINCIPLES OF ANIMAL RESEARCH FOR GRADUATE AND UNDERGRADUATE STUDENTS
Subtítulo:
Autor:
MARK SUCKOW KAY STEWART
Editorial:
ACADEMIC PRESS
Año de edición:
2016
Materia
MÉTODOS
ISBN:
978-0-12-802151-4
Páginas:
286
Tamaño:
190 x 235
Disponibilidad:
Disponible
99,95 € Comprar

Sinopsis

Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all aspects of the research experience, including the research and development of a thesis, model selection, experimental design, IACUC protocol preparation, and animal husbandry and technical procedural needs, the book is a necessary addition to every student, technician, and researcher’s education.

Key Features

Provides background material for students to understand the broader backdrop against which animal research is undertaken
Includes ethical and regulatory information
Covers commonly used animal models and the process to choose a model for biomedical research

Readership

Early researchers, undergraduate and graduate students, researchers and professors studying laboratory animal research; technicians in laboratory animal science; pre-veterinarians and veterinarians; and students/early researchers working with laboratory animals across biological and biomedical research

Índice

Preface
Chapter 1. Brief Historical Overview on the Use of Animals in Research
1.1. Introduction
1.2. Early Attitudes Toward Animal Health and Disease
1.3. Development and Emergence of New Animal Models
1.4. Improvements in Approaches to Animal Care
1.5. Summary
Chapter 2. Philosophical and Ethical Foundations
2.1. Basic Approaches
2.2. Animal Welfare Versus Animal Rights
2.3. Opposition to and Benefits of Animal Experimentation
2.4. Professional Ethics Relating to Biomedical Research
Chapter 3. Regulations and Guidelines
3.1. Introduction
3.2. US Animal Welfare Act
3.3. Public Health Service Policy
3.4. FDA Good Laboratory Practices
3.5. Other Laws, Regulations, and Policies
3.6. Fish and Wildlife Service and NIH Positions on Chimpanzees
3.7. Professional and Scientific Associations
3.8. International Laws and Regulations
3.9. Conclusions
Chapter 4. Institutional Animal Care and Use Committee
4.1. Purpose and Function
4.2. Committee Composition
4.3. IACUC Review of Proposed Activities and Projects
4.4. Periodic Review of the Animal Care and Use Program and Facilities
4.5. Investigation of Concerns Regarding the Use and Treatment of Vertebrate Animals
4.6. Sample Size Estimation in Laboratory Animal Experiments
Chapter 5. Experimental Variables
5.1. The Research Environment
5.2. Environmental Enrichment
5.3. Animal Health Monitoring Program
5.4. Summary
Chapter 6. Model Selection
6.1. Selection Criteria
6.2. Types of Models
6.3. Spontaneous Mutation Models
6.4. Random Mutation Models
6.5. Genetically Manipulated Models
6.6. Chemically Induced Models
6.7. Physically Induced Models
6.8. Surgical Models
6.9. Behavioral Models
6.10. Production Models
Chapter 7. Commonly Used Animal Models
7.1. The Mouse
7.2. The Rat
7.3. The Rabbit
7.4. Zebrafish
7.5. Amphibians and Reptiles
7.6. Birds
7.7. Other Small Mammals
7.8. Summary
Chapter 8. Common Technical Procedures in Rodents
8.1. Handling and Restraint Methods
8.2. Identification
8.3. Common Technical Procedures
8.4. Rodent Anesthesia
8.5. Rodent Surgery
8.6. Euthanasia
8.7. Necropsy
8.8. Summary
Chapter 9. Considerations for Use of Vertebrates in Field Studies
9.1. Reasons for Conducting Field Research
9.2. Sources for Specific Technique Information
9.3. Initial Steps for Undertaking Field Research Involving Vertebrates
9.4. Observational Techniques
9.5. Capturing Animals
9.6. Handling Animals
9.7. Identification and Marking of Animals
9.8. Conclusion
Chapter 10. Personnel Safety in the Care and Use of Laboratory Animals
10.1. Introduction
10.2. Occupational Health and Safety Programs
10.3. Hazards Associated With Animal Research
10.4. Best Practices for Prevention
10.5. Conclusions: Personnel Engagement and Awareness
Chapter 11. Thesis Development
11.1. Preparation
11.2. Thesis Sections
11.3. Finalizing the Thesis
11.4. Conclusion
Glossary of Terms and Acronyms
Index